The cell cycle rallies the transcription cycle
نویسندگان
چکیده
منابع مشابه
The elusive cell cycle–transcription link
The elusive cell cycle– transcription link cientists have known for years that transcription is repressed as cells enter mitosis, yet the mechanistic bridge between the two processes has eluded detection. Now, Jian Chen, Beat Suter (McGill University, Montreal, Canada), and colleagues find that Xpd, a component of the general transcription factor complex, TFIIH, regulates another member of the ...
متن کاملSingle-cell analysis of transcription kinetics across the cell cycle.
Transcription is a highly stochastic process. To infer transcription kinetics for a gene-of-interest, researchers commonly compare the distribution of mRNA copy-number to the prediction of a theoretical model. However, the reliability of this procedure is limited because the measured mRNA numbers represent integration over the mRNA lifetime, contribution from multiple gene copies, and mixing of...
متن کاملCell cycle: Driving the centrosome cycle
Cyclin-dependent kinases (Cdks) control major transitions as cells pass through the cell cycle. It has recently been shown that centrosome duplication in vertebrates requires Cdk2 activity and can be driven solely by Cdk2-cyclin E complexes.
متن کاملCell cycle-regulated transcription in fission yeast.
A fundamental process in biology is the mechanism by which cells duplicate and divide to produce two identical daughter cells. The fission yeast, Schizosaccharomyces pombe, has proved to be an excellent model organism to study the role that gene expression plays in this process. The basic paradigm emerging is that a number of groups of genes are expressed in successive waves at different cell c...
متن کاملTranscription Regulatory Networks in Yeast Cell Cycle
Introduction The functional genomics techniques for mapping transcription regulatory networks have evolved based on advances in experimental approaches and the kinds of data generated. Studies in yeast have emphasized powerful genetic approaches that are not available in other higher eukaryotic organisms. As a consequence, yeast is particularly amenable for analyzing transcriptional regulatory ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Transcription
سال: 2013
ISSN: 2154-1264,2154-1272
DOI: 10.4161/trns.22456